The genome polishing tool POLCA makes fast and accurate corrections in genome assemblies

Aug 18, 2020 1 min read 👏

Publishing date: 2020-08-18

Published on: PLOS Computational Biology

summary: In this report, Zimin and Salzberg present the assembly polishing tool POLCA (POLishing by Calling Alternatives) and compare its performance with two other popular polishing programs, Pilon and Racon. They show that on simulated data POLCA is more accurate than Pilon, and comparable in accuracy to Racon. On real data, all three programs show similar performance, but POLCA is consistently much faster than either of the other polishing programs.

authors: Aleksey V. Zimin, Steven L. Salzberg

link to paper: 10.1371/journal.pcbi.1007981

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