Featured research

AlbaTraDIS: Comparative analysis of large datasets from parallel transposon mutagenesis experiments

Publishing date: 2020-08-18 Published on: PLOS Computational Biology summary: In this software paper, Page et al develop ‘AlbaTraDIS’; a software application for rapid large-scale comparative analysis of TraDIS experiments that predicts the impact of transposon insertions on nearby genes.

OSS-DBS: Open-source simulation platform for deep brain stimulation with a comprehensive automated modeling

Publishing date: 2020-08-18 Published on: PLOS Computational Biology summary: In this study, Butenko et al propose a new open-source simulation platform that comprises computer-aided design and computer-aided engineering tools for highly automated evaluation of electric field distribution and neural activation during Deep Brain Stimulation (DBS).

RefShannon: A genome-guided transcriptome assembler using sparse flow decomposition

Publishing date: 2020-08-18 Published on: PLOS ONE summary: High throughput RNA-Seq has become a staple in modern molecular biology, with applications not only in quantifying gene expression but also in isoform-level analysis of the RNA transcripts.

The genome polishing tool POLCA makes fast and accurate corrections in genome assemblies

Publishing date: 2020-08-18 Published on: PLOS Computational Biology summary: In this report, Zimin and Salzberg present the assembly polishing tool POLCA (POLishing by Calling Alternatives) and compare its performance with two other popular polishing programs, Pilon and Racon.

Development of a low-cost, user-customizable, high-speed camera

Publishing date: 2020-06-15 Published on: PLOS ONE summary: Channel Editor Summary: The paper describes a high speed camera system, capable of reaching frame rates of ~2300 frames per second in its max speed setting.