PLOS ONE

PhyloPi: An affordable, purpose built phylogenetic pipeline for the HIV drug resistance testing facility

Publishing date: 2019-03-05 Published on: PLOS ONE summary: None authors: Phillip Armand Bester, Andrie De Vries, Stephanus Riekert, Kim Steegen, Gert van Zyl, Dominique Goedhals link to paper: 10.1371/journal.pone.0213241 Icons made by catkuro from www.

EMBL2checklists: A Python package to facilitate the user-friendly submission of plant and fungal DNA barcoding sequences to ENA

Publishing date: 2019-02-27 Published on: PLOS ONE summary: The submission of DNA sequences to public sequence databases is an essential, but insufficiently automated step in the process of generating and disseminating novel DNA sequence data.

Open-source automated chemical vapor deposition system for the production of two- dimensional nanomaterials

Publishing date: 2019-02-01 Published on: PLOS ONE summary: The study of two- dimensional (2D) materials is a rapidly growing area within nanomaterials research. However, the high equipment costs, which include the processing systems necessary for creating these materials, can be a barrier to entry for some researchers interested in studying these novel materials.

Validating quantum-classical programming models with tensor network simulations

Publishing date: 2019-01-17 Published on: PLOS ONE summary: The exploration of hybrid quantum-classical algorithms and programming models on noisy near-term quantum hardware has begun. As hybrid programs scale towards classical intractability, validation and benchmarking are critical to understanding the utility of the hybrid computational model.

Cell colony counter called CoCoNut

Publishing date: 2018-12-20 Published on: PLOS ONE summary: CoCoNut removes the need for slow and eye-straining manual counting of viable colonies under a microscope. It’s a semi-automated, image-based cell colony counting setup that combines 3D-printed hardware and an ImageJ plugin.

Open-source sensor for measuring oxygen partial pressures below 100 microbars

Publishing date: 2018-12-20 Published on: PLOS ONE summary: This nifty device measures partial pressure of oxygen in a similar manner to commercial devices, yet at substantially reduced cost. In a nutshell, a sinusoidally modulated LED excites a luminescent dye over time, while a photodiode picks up the spectrally shifted emission light from the dye.

A large-scale analysis of bioinformatics code on GitHub

Publishing date: 2018-12-10 Published on: PLOS ONE summary: In recent years, the explosion of genomic data and bioinformatic tools has been accompanied by a growing conversation around reproducibility of results and usability of software.

An open-source k-mer based machine learning tool for fast and accurate subtyping of HIV-1 genomes

Publishing date: 2018-12-10 Published on: PLOS ONE summary: The classification of infections is a routine component of clinical management. Kameris is an open source toolkit for a supervised and alignment-free subtyping method which operates on HIV-1 sequences.

Assessing a novel way to measure step count while walking using a custom mobile phone application

Publishing date: 2018-12-10 Published on: PLOS ONE summary: Walking speed has been associated with many clinical outcomes (e.g., frailty, mortality, joint replacement need, etc.). Accurately measuring walking speed (stride length x step count/time) typically requires significant clinician/staff time or a gait lab with specialized equipment (i.

Design and validation of an open-source modular Microplate Photoirradiation System for high-throughput photobiology experiments

Publishing date: 2018-11-19 Published on: PLOS ONE summary: This paper presents a useful open-source Microplate Photoirradiation System (MPS) for use in standard 96- and 24-well microplates that allows photobiologists to conduct a variety of experiments in a high-throughput format, inlcuding inside incubators.